01/02/2025

Top 200 Drugs Fast Pace Edition: Potassium Sparing Diuretics (-actone)

Potassium-Sparing Diuretics Overview

What are they?
Medications that help the body remove excess fluid while retaining potassium, preventing potassium loss commonly caused by other diuretics.

How to recognize them?
Common examples include spironolactone, eplerenone, amiloride, and triamterene.

How do they work?
Block sodium reabsorption in the kidneys → Reduce fluid buildup → Maintain potassium levels.

Easy trick to remember:
"Potassium Stays Put" (Unlike other diuretics, these help retain potassium).

Common uses:

  • High blood pressure

  • Heart failure

  • Edema (fluid retention)

  • Hormonal conditions (e.g., spironolactone for PCOS)

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