01/02/2025

Top 200 Drugs Fast Pace Edition: Potassium Sparing Diuretics (-actone)

Potassium-Sparing Diuretics Overview

✔ What are they?
Medications that help the body remove excess fluid while retaining potassium, preventing potassium loss commonly caused by other diuretics.

✔ How to recognize them?
Common examples include spironolactone, eplerenone, amiloride, and triamterene.

✔ How do they work?
Block sodium reabsorption in the kidneys → Reduce fluid buildup → Maintain potassium levels.

✔ Easy trick to remember:
"Potassium Stays Put" (Unlike other diuretics, these help retain potassium).

✔ Common uses:

  • High blood pressure

  • Heart failure

  • Edema (fluid retention)

  • Hormonal conditions (e.g., spironolactone for PCOS)

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